Veep follows former Senator-turned-Vice President Selina Meyer (Louis-Dreyfus), who discovers her position in the White House isn't what she expected.
Although Louis-Dreyfus descrives Meyer as "not as chic as Michelle Obama", she told People that her wardrobes are inspired by the US First Lady "so we can move it slightly away from the square look - no offense".
Louis-Dreyfus also expressed her admiration for Obama, who she considers her "icon".
"I adore her," she added. "Oh my God, look how she puts the belt around the sweater! I don't feel as though I'm as cool as she is."
The former Seinfeld actress previously revealed that viewers will never know what political party Meyer represents and the president will not make an appearance.
Veep premieres tonight (April 22) at 10pm ET on HBO.
Watch the trailer for Veep below: